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CPAC
BACKGROUND |
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The Center for Process Analytical
Chemistry (CPAC) is a self-sustaining
organization, with a successful consortium of sponsors recruited from
all sectors of industry.
The present CPAC program can be summarized by
two main components:
· new measurement
approaches including the miniaturization of traditional
instrumentation and the development of new sensors and non-traditional
instruments,
· mechanisms for
interaction, collaboration, and communication of Center activities,
research programs, and information related to process analytical
technology (PAT)
among sponsors, other universities and academic departments,
government agencies, and the general measurement and control
community. CPAC has an established track record in fostering
academic/industrial/national laboratory interactions, which aim at
bridging the gap between basic research and full-scale process/product
development.
Within CPAC, the following sponsor focus
groups serve as a forum for
discussion and guidance concerning the industrial relevance of CPAC
research projects. |
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Industrial: |
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Materials & Chemical Processes
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Oil & Petrochemicals
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Food & Consumer Products
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Pharmaceuticals & Biotechnology |
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Technical: |
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Chemometrics
·
Process Optimization/Control
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Spectroscopy/Imaging |
·Chromatography
·
Sensors |
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CPAC
INITIATIVES AND PLATFORM PROJECTS |
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·
Fermentation Monitoring (FermI)
The optimization of bio-reactors is of
importance due to the value of industrial bio-technology, as well as
the increasing interest in bio-fuels and bio-sustainability.
CPAC is involved with several research projects to develop measurement
tools that will compliment existing monitoring methods and allow for
studies to optimize bio-reactions and related process control. |
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Micro-Reactors and Instrumentation |
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Several CPAC Research Projects are
emphasizing micro-analytical and micro-sensor development. |
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New Sampling/Sensor Initiative (NeSSI™)-
see description below |
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PERSONNEL |
| Faculty Director |
·
Rob Synovec |
| Executive Director |
·
Mel Koch |
| Adm. Manager |
·
Nan Holmes |
| UW, Chemistry |
·
Anatol Brodsky
·
Lloyd Burgess
·
Daniel Chiu |
·
Norm Dovichi
·
Scott Gilbert
·
Robert Synovec |
| UW, Applied Physics Laboratory
(APL) |
| ·
Brian Marquardt |
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| UW, Electrical Engineering |
·
Alex Mamishev
·
Brian Otis |
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Babak Parviz
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Tim Strovas |
| UW, Forest Resources |
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Richard Gustafson
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Sharon Doty |
·
Renata Bura
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Ray Chrisman |
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UW, Mechanical Engineering |
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Joyce Cooper |
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UW, Medical Genetics |
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Clement Furlong |
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Scott Soelberg |
| U. of St. Thomas |
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·
Anthony Borgerding |
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| U. of Maine |
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Scott Collins |
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| U. of Minnesota |
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Kent Mann |
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| U. of California -- Davis |
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Sandra Garcia
·
Michael McCarthy |
·
Jeffrey de Ropp
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Jeffrey Walton |
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Visiting Scholars |
| ·
Sergey Mozharov |
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PERSONNEL
DISTRIBUTION: |
UW PI's
Grad Students
Staff |
20
17
2 |
Off Site PIs
Post-Docs
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6
2
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INDUSTRIAL
ADVISORY BOARD |
| CPAC presently has 12 Full
Sponsor organizations, each having a seat on the Industrial Advisory Board (IAB) that
helps guide CPAC research and operations. CPAC also has 17 Associate
(Vendor/Instrumentation) Sponsors to aid in the technology
transfer/commercialization of CPAC technology. |
| IAB
Chair |
Jeff Gunnell,
ExxonMobil |
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Past Chair |
Carl Rechsteiner,
Chevron |
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Chair Elect |
Paul Vahey, Boeing |
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RESEARCH
PROJECTS |
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Sensors: |
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Advanced Sensors for Process Analysis,
Burgess/Synovec |
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·
Enhancement of Small Molecule
Detection for Near Real-Time Process Analysis Using Magnetic
Nanoparticles, Furlong |
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Vapochromic Detection and
Identification of Important Analytes, Mann/Marquardt |
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Modular Sensing Architecture for
Low-Cost
Wireless Monitoring,
Parviz/Otis |
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Spectroscopy/Imaging:
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·NEW
Energy Impact of CPAC Technologies, Mamishev |
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Evaluating Raman Spectroscopy to
Improve Process Monitoring and Materials Characterization,
Marquardt /Bura/Gustafson/Chrisman |
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Investigating the Use of LIBS as an
Effective Process Analysis Tool, Marquardt |
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Improving the Sensitivity of Nuclear
Magnetic Resonance for Process Analysis,
McCarthy/Garcia/Walton/Collins/Han |
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Chromatography: |
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·
NEW
Process Monitoring with Microdialysis Extraction and Gas
Chromatography, Borgerding/Synovec |
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Process Liquid Chromatography:
Engineering of NeSSI™
Sampling System Platform for
Fast on-Line HPLC Process Monitoring, Synovec/Burgess/Gilbert |
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Process Gas Chromatography and
Chemometrics,
Synovec/Rohrback/Ramos |
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Process Optimization and Control: |
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·NEW
Endophyte-Assisted Phytoremediation of PAH's using Willow, Doty
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The Use of
Microreactors and NeSSI™
for Characterizing Chemistry and Developing Effective Chemical
Processes, Marquardt/Schwartz/Gustafson |
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Bio-Analytical |
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·Droplet-Based
Analytical Devices, Chiu |
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·Microreactor-Based
Assays, Dovichi |
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·NEW
A Nanopure Microprobe for Electronic Analysis of Nanoparticles,
Zhang |
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Bio-Energy
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·Development
of Sensors for Hydrolysis of Cellulosic Biomass to Sugars,
Bura/Gustafson/Marquardt |
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·Super
Critical Water Gasification of Biomass, Cooper |
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·Application of Novel Membranes for
Separation and Concentration in Lignocellulosic Biorefineries,
Gustafson/Bura/Marquardt/Chrisman |
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